Let's start by saying everyone is different, not everyone takes the same dosage. Taking CBD is finding the dosing that works for you. We start everyone off at .25ml. After a couple days you will find out what your body needs. If your body needs more, you will go up to .50ml. If your body needs less, you will experience a pressure helmet headache. The main thing about taking CBD is consistency. When taking Natural Wellness CBD product’s, we highly recommend that you take the tincture morning and night. If you have any questions please feel free to reach out to any of our locations, or simply send us a message on here.